Document Detail


Induction-intubation response--smokers vs non-smokers--.
MedLine Citation:
PMID:  16381259     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVES: Tobacco smoking has been established to be a hazardous activity. Changing social attitude is bringing a decline in tobacco consumption but a significant proportion of patients presenting for surgery still continues to smoke, putting themselves at risk of perioperative complications. We evaluated induction-intubation response in 40 male patients (ASA-I) divided into two groups of 20, each consisting of smokers and non-smokers.
METHODS: All patients received standard premedication and general anesthesia. Heart rate, blood pressure and rate-pressure product were measured prior to induction, just before intubation and at 1, 3, 5 and 10 minutes after intubation. Continuous electrocardiography (EKG lead II) monitoring was done. Carboxyhemoglobin and total hemoglobin were estimated at the time of securing venous access. Arterial blood gases were analysed 5 minutes before and after the tracheal intubation.
RESULTS: Incidence of arrhythymias (30%) was higher in smokers compared to non-smokers (10%). Mean carboxyhemoglobin (COHb) level in smokers was 3.81 +/- 2.17 gdL(-1) as compared to 2.95 +/- 1.33 gdL(-1) in non-smokers. Four patients who continued to smoke till the day of surgery had higher COHb levels (8.2, 5.9, 6, 8.8 gdL(-1)). PaO2 and PaCO2 levels were comparable in both groups.
CONCLUSIONS: During induction-intubation period, heart rate; systolic, diastolic and mean arterial pressure and rate-pressure product showed more pronounced fluctuations in smokers than in non-smokers (p < 0.05).
Authors:
S K Malhotra; S Singh; A Bajaj; N Varma; A Kumar; D Nakra
Related Documents :
2524949 - A study of epidural morphine and sufentanil anesthesia for abdominal aortic surgery.
1446399 - A comparative study of propofol and thiopental as induction agents for elective caesare...
475109 - Hemodynamic effects of unilateral segmented lumbar epidural analgesia in cattle.
2368889 - The haemodynamic effects of propofol and thiopentone for induction of caesarean section.
23612619 - Comparison of haemodynamic effects of noninvasive ventilation delivered via resqgard an...
11531679 - The effect of prophylactic metaraminol on systemic hypotension caused by induction of a...
758389 - Assessment of patent ductus arteriosus shunting using diastolic pressure analysis.
8622249 - Choice of initial therapy for hypertension.
1501209 - Tiletamine hydrochloride in combination with zolazepam hydrochloride as an anaesthetic ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Middle East journal of anaesthesiology     Volume:  18     ISSN:  0544-0440     ISO Abbreviation:  Middle East J Anaesthesiol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-12-29     Completed Date:  2006-02-21     Revised Date:  2014-10-10    
Medline Journal Info:
Nlm Unique ID:  8604187     Medline TA:  Middle East J Anaesthesiol     Country:  Lebanon    
Other Details:
Languages:  eng     Pagination:  529-40     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, General*
Arrhythmias, Cardiac / etiology
Blood Pressure
Carboxyhemoglobin / analysis
Heart Rate
Humans
Intraoperative Complications / etiology
Intubation, Intratracheal*
Male
Smoking* / adverse effects
Chemical
Reg. No./Substance:
9061-29-4/Carboxyhemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Does pancuronium or cisatracurium delay the rate of arousal following remifentanil-based anesthesia?
Next Document:  The challenge of a multicultural environment for critical care nursing in Saudi Arabia.