Document Detail


Induction of hepatomas secreting large amounts of alpha-fetoprotein.
MedLine Citation:
PMID:  70269     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hepatomas secreting large amounts of alpha-fetoprotein were induced in Fischer rats by the continuous feeding of 0.06% 3'-methyl-4-dimethylaminoazobenzene. Serum alpha-fetoprotein concentrations in the 59 hepatoma-bearing rats ranged from 92--3260 microgram/ml (mean, 972 microgram/ml; median, 830 microgram/ml) at the time of primary tumor transplantation.
Authors:
C J Smith; P C Kelleher
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cancer letters     Volume:  3     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-10-20     Completed Date:  1977-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  53-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carcinoma, Hepatocellular / chemically induced,  secretion*
Liver Neoplasms / chemically induced,  secretion*
Methyldimethylaminoazobenzene
Neoplasms, Experimental / chemically induced,  secretion
Rats
alpha-Fetoproteins / secretion*
Chemical
Reg. No./Substance:
0/alpha-Fetoproteins; 55-80-1/Methyldimethylaminoazobenzene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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