Document Detail

Induction of hair growth in alopecia areata with D.N.C.B.
MedLine Citation:
PMID:  72899     Owner:  NLM     Status:  MEDLINE    
43 patients with alopecia areata were treated with weekly applications of dinitrochlorobenzene (D.N.C.B.), dissolved in acetone, on one side of the head, with the other side serving as control region. The therapeutic aim was a mild contact dermatitis. A significant difference of hair growth between the treated and untreated sides was observed in 33 patients. 21 patients showed regrowth of hair exclusively on the treated side, and in 12 patients regrowth was considerably faster and more dense on the treated side. In the majority of patients the difference was noted within 3 months.
R Happle; K Echternacht
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1002-3     Citation Subset:  AIM; IM    
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MeSH Terms
Administration, Topical
Alopecia Areata / drug therapy*
Dermatitis, Contact / chemically induced
Dinitrochlorobenzene / administration & dosage,  therapeutic use*
Drug Evaluation
Middle Aged
Nitrobenzenes / therapeutic use*
Reg. No./Substance:
0/Nitrobenzenes; 97-00-7/Dinitrochlorobenzene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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