| Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex. | |
| | |
MedLine Citation:
|
PMID: 21451358 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Traumatic brain injury promotes rapid induction of microglial cells and infiltration of peripheral macrophages to the injury sites. Such inflammatory responses are mediated by the activation and migration of immune cells, which are influenced by the actin cytoskeleton remodeling. In this study, we observed that the phosphorylation and expressions of ezrin-radixin-moesin (ERM) proteins, which are linkers for cell surface with actin cytoskeleton, are induced in the activated microglia/macrophages, whereas ERM molecules are only marginally expressed in quiescent microglia in the normal brain. These results suggest that ERM activation in the injury penumbra is implicated in the inflammatory immune responses after traumatic brain injury. |
| | |
Authors:
|
Younghye Moon; Joo Yeon Kim; So Yoen Choi; Kyungjin Kim; Hyun Kim; Woong Sun |
Related Documents
:
|
3933518 - Effects of 1-hydroxyethylidene-1,1 bisphosphonate and (chloro-4 phenyl) thiomethylene b... 21296978 - Immunization with live and dead chlamydia muridarum induces different levels of protect... 21481488 - From virus to inflammation: mechanisms of rig-i-induced il-1β production. 11673558 - Cross-talk between il-1 and il-6 signaling pathways in rheumatoid arthritis synovial fi... 9808068 - Ethanol modulates induction of nitric oxide synthase in glial cells by endotoxin. 9928498 - Animal models and in vitro models for the study of aetiopathogenesis of spondyloarthrop... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neuroreport Volume: 22 ISSN: 1473-558X ISO Abbreviation: Neuroreport Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-03-31 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9100935 Medline TA: Neuroreport Country: England |
Other Details:
|
Languages: eng Pagination: 304-8 Citation Subset: IM |
Affiliation:
|
aDepartment of Anatomy and Division of Brain Korea 21 Biomedical Science, Korea University College of Medicine bBrain and Neuroendocrine Laboratory, School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Segregation of gustatory cortex in response to salt and umami taste studied through event-related po...
Next Document: Nesfatin-1 stimulates renal sympathetic nerve activity in rats.