Document Detail


Induction of estrus by prostaglandin F2alpha administration in the vaginal vestibules of miniature pigs.
MedLine Citation:
PMID:  16543698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Estrus induction is an important step in embryo production. It has been difficult to induce estrus in miniature pigs by intramascular (i.m.) injection of prostaglandin F2alpha (PGF2(2alpha)) in the early luteal stage of the estrous cycle. In the present study, we injected two different doses of PGF2(2alpha) i.m. and into the submucosa of the vaginal vestibule (i.ves.) of miniature pigs, and examined the effect of these treatments on estrus induction. Fifteen miniature pigs were divided into five experimental groups (control, saline injected i.m.; PGF2alpha treated, 1.0 or 1.5 mg of PGF2alpha injected twice i.m. or i.ves.), and the estrus length and concentrations of 17beta-estradiol (E2) and progesterone (P) in the blood were examined. Estrus length was significantly shortened by a large amount of PGF2alpha injected i.ves. In addition, the concentration of P in the blood significantly decreased after two injections of PGF2alpha (i.m. or i.ves.). These results suggest that in miniature pigs, administration of at least 3.0 mg of PGF2alpha is required for the induction of luteolysis and injection of PGF2alpha into the vaginal vestibule is a useful method of estrus induction.
Authors:
Takeshi Kuge; Hisataka Iwata; Takehito Kuwayama; Ikuo Domeki; Yasuo Shioya; Yasunori Monji
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Publication Detail:
Type:  Journal Article     Date:  2006-03-15
Journal Detail:
Title:  The Journal of reproduction and development     Volume:  52     ISSN:  0916-8818     ISO Abbreviation:  J. Reprod. Dev.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-28     Completed Date:  2006-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9438792     Medline TA:  J Reprod Dev     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  391-6     Citation Subset:  IM    
Affiliation:
Laboratory of Animal Reproduction, Department of Animal Science, Tokyo University of Agriculture, Japan.
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MeSH Terms
Descriptor/Qualifier:
Administration, Intravaginal
Animals
Dinoprost / administration & dosage*,  pharmacology*
Estradiol / blood
Estrus / drug effects*
Female
Luteolysis
Progesterone / blood
Swine
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 551-11-1/Dinoprost; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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