Document Detail

Induction at 41 weeks increases the risk of caesarean section in a hospital with a low rate of caesarean sections.
MedLine Citation:
PMID:  23035749     Owner:  NLM     Status:  Publisher    
Abstract Objective: The objective of this study was to compare the effects of two betamethasone dosage regimens on selected parameters in mothers and on the status of the preterm newborn. Methods: The analysis included 121 patients who gave birth by gestational week 35 and within 7 days after the completion of a full course of steroid treatment (24 mg). The study group consisted of 45 patients receiving six 4-mg doses of betamethasone every 8 hours. The control group consisted of 76 patients receiving two 12-mg doses of betamethasone separated by 24 hours. Results: After treatment, a significant increase in the leukocyte count was observed in the control group. Significant reductions in the erythrocyte counts, hemoglobin levels and hematocrit after treatment were also found in the control group. The post-natal status of newborns did not differ significantly between groups. The betamethasone dosage regimen used did not affect the incidence of moderate and severe respiratory disorders, IVH, NEC, retinopathy, infection, hyperbilirubinemia or anemia in neonates. Mild respiratory disorders were slightly more common in the study group. Conclusion: A reduction in the single steroid dose administered to patients at risk of premature birth may reduce maternal side effects.
Ewa Romejko-Wolniewicz; Luiza Oleszczuk; Julia Zaręba-Szczudlik; Krzysztof Czajkowski
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-4
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
II Department of Obstetrics and Gynaecology, Warsaw Medical University, Warsaw, Poland.
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