Document Detail

Induction of HLA-DQ antigen expression on a human promyelocytic leukemia cell line HL-60.
MedLine Citation:
PMID:  2741648     Owner:  NLM     Status:  MEDLINE    
A variant strain of HL-60, which is positive for HLA-DR antigen, was induced to express HLA-DQ antigen following treatment with phorbol esther. It was preceded by cell cycle arrest in the G1 phase and was accompanied by augmented phagocytosis. This differential expression of HLA class II antigens on this subline may contribute to understanding the functional role of HLA class II antigens in the hematopoietic differentiation of macrophage cells.
S Onisawa; T Ichimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society     Volume:  52     ISSN:  0001-5806     ISO Abbreviation:  Nippon Ketsueki Gakkai Zasshi     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-08-10     Completed Date:  1989-08-10     Revised Date:  2011-07-28    
Medline Journal Info:
Nlm Unique ID:  2984803R     Medline TA:  Nihon Ketsueki Gakkai Zasshi     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  25-31     Citation Subset:  IM    
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MeSH Terms
Cell Cycle
Cell Line
HLA-DQ Antigens / analysis*
Leukemia, Promyelocytic, Acute / immunology*
Phorbol Esters / pharmacology
Reg. No./Substance:
0/HLA-DQ Antigens; 0/Phorbol Esters

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