Document Detail


Induced osteogenesis in the repair of experimental mandibular defects in rats.
MedLine Citation:
PMID:  7016947     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to investigate the repair of mandibular defects, we have devised a nonhealing model in the ramus of the rat mandible. The large full thickness defects, devoid of periosteum, were filled with demineralized bone powder (DBP), lyophilized bone chips, and un-demineralized bone powder (BP) or were irrigated with Ringer's lactate. Healing was judged by gross and histologic examination and by incorporation fo 45 calcium into hydropyapatite. DBP produced more rapid and complete healing than did BP or lyophilized chips. DBP did not undergo appreciable resorption prior to bone formation and was a more potent osteogenic stimulus than was BP or lyophilized chips.
Authors:
L B Kaban; J Glowacki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dental research     Volume:  60     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-08-20     Completed Date:  1981-08-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1356-64     Citation Subset:  D; IM; S    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone Transplantation*
Decalcification Technique
Freeze Drying
Male
Mandible / anatomy & histology,  physiology*
Mandibular Diseases / surgery*
Osteogenesis*
Rats
Tissue Preservation
Transplantation, Isogeneic
Wound Healing

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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