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Induced hypothermia as a neuroprotectant in post-cardiac arrest.
MedLine Citation:
PMID:  21603454     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Survivors of out-of-hospital cardiac arrest frequently suffer devastating effects from anoxic brain injury. Therapeutic hypothermia is the first therapy to show benefit in improving survival as well as limiting neurologic injury. We review the data supporting the use of therapeutic hypothermia in this patient population, the pathophysiologic basis of its neuroprotectant effects, the methods of hypothermic induction, and the clinical application.
Authors:
Mohi E Alkadri; Paul McMullan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Ochsner journal     Volume:  9     ISSN:  1524-5012     ISO Abbreviation:  Ochsner J     Publication Date:  2009  
Date Detail:
Created Date:  2011-05-23     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101125795     Medline TA:  Ochsner J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-81     Citation Subset:  -    
Affiliation:
Department of Cardiology, Ochsner Clinic Foundation, New Orleans, LA.
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