| Induced hyperosmolality effects on extracellular fluid volume, lymph flow and osmolar equilibrium: studies in the rat. | |
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MedLine Citation:
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PMID: 6820232 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of experimentally induced hyperosmolality has been studied in rats. Renal vascular pedicle ligation was performed on all animals to prevent renal clearance of the infused solute, xylose, and allow accurate ECF space determinations with 51Cr EDTA. Small volume hyperosmolar xylose infusions caused parallel elevation of the osmolality of thoracic duct lymph and arterial plasma. A positive correlation was obtained between lymph osmolality and flow alterations. The maximal osmolality elevation of 22 mosm X kg-1 H2O was associated with an intracellular fluid mobilisation which was equal to 7.1% of the ECF space. The infused and mobilised fluid volumes were distributed unequally between the intra and extra vascular compartments of the ECF. |
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Authors:
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J Ware; G Quiros; K A Norberg; G Nylander |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta physiologica Scandinavica Volume: 116 ISSN: 0001-6772 ISO Abbreviation: Acta Physiol. Scand. Publication Date: 1982 Nov |
Date Detail:
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Created Date: 1983-05-05 Completed Date: 1983-05-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370362 Medline TA: Acta Physiol Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 223-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Edetic Acid / pharmacology Extracellular Space / physiology* Iodohippuric Acid / pharmacology Lymph / physiology* Male Osmolar Concentration* Rats Rats, Inbred Strains Xylose / analysis, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Xylose; 147-58-0/Iodohippuric Acid; 60-00-4/Edetic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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