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Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences.
MedLine Citation:
PMID:  22935022     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Induced pluripotent stem (iPS) cells, are a type of pluripotent stem cell derived from adult somatic cells. They have been reprogrammed through inducing genes and factors to be pluripotent. iPS cells are similar to embryonic stem (ES) cells in many aspects. This review summarizes the recent progresses in iPS cell reprogramming and iPS cell based therapy, and describe patient specific iPS cells as a disease model at length in the light of the literature. This review also analyzes and discusses the problems and considerations of iPS cell therapy in the clinical perspective for the treatment of disease.
Authors:
Lei Ye; Cory Swingen; Jianyi Zhang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-27
Journal Detail:
Title:  Current cardiology reviews     Volume:  -     ISSN:  1875-6557     ISO Abbreviation:  Curr Cardiol Rev     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101261935     Medline TA:  Curr Cardiol Rev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Medicine, University of Minnesota, USA. ylei@umn.edu.
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