| Indoprofen versus indomethacin and placebo. A double-blind three-way cross-over trial in rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 7042365 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty in-patients suffering from classical or definite R.A. were given indoprofen 200 mg q.i.d., indomethacin 25 mg q.i.d. and placebo, according to a 6-line completely balanced block design. Each patient received the three treatments for ten days each. Patients were examined at baseline and after each treatment cycle. Both active drugs were significantly better than placebo on relief of pain, Ritchie index, and number of active, painful and swollen joints, morning stiffness; only indoprofen significantly improved grip strength. No significant differences were found between the two active drugs. The three treatments were well tolerated. |
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Authors:
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M Nissilä; S Jalava; W Groppi |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: European journal of rheumatology and inflammation Volume: 4 ISSN: 0140-1610 ISO Abbreviation: Eur J Rheumatol Inflamm Publication Date: 1981 |
Date Detail:
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Created Date: 1982-07-19 Completed Date: 1982-07-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7805765 Medline TA: Eur J Rheumatol Inflamm Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 74-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Analysis of Variance Arthritis, Rheumatoid / drug therapy* Clinical Trials as Topic Double-Blind Method Drug Administration Schedule Female Humans Indomethacin / therapeutic use* Indoprofen / therapeutic use* Male Middle Aged Phenylpropionates / therapeutic use* Placebos |
| Chemical | |
Reg. No./Substance:
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0/Phenylpropionates; 0/Placebos; 31842-01-0/Indoprofen; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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