Document Detail

Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China.
MedLine Citation:
PMID:  15350953     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Information on indoor allergen exposures among non-Western populations, which have lower prevalence of atopic illness, is scant. We examined whether exposures to common indoor allergens were associated with doctor-diagnosed asthma and asthma-related symptoms among Chinese adolescents.
METHODS: A cross-sectional study of 4,185 ninth grade students was conducted at 22 randomly selected schools in Wuhan, China. Information on respiratory health and exposures to indoor allergens was obtained by a self-administered questionnaire completed in class.
RESULTS: Having animals currently was associated with persistent cough [prevalence odds ratio (POR)=1.54, 95% confidence interval (CI ): 1.21-2.11] and wheeze (POR=1.41, 95% CI: 1.03-1.94). Early-life exposure to animals was also associated with doctor-diagnosed asthma (POR=1.95, 95% CI: 1.35-2.82). Associations with respiratory symptoms strengthened with higher levels of exposure and for exposure in both early childhood and in adolescence. Exposure to cockroaches and having mold/water damage in the home contributed especially to wheezing (POR=2.03, 95% CI: 1.41-2.90 for cockroaches; POR=2.49, 95% CI: 1.82-3.40 for mold/water damage).
CONCLUSIONS: Indoor allergen exposures were positively associated with asthma diagnosis and persistent respiratory symptoms among Chinese adolescents. Neither early-life nor current exposure to animals was protective for asthma or asthma-related symptoms.
Päivi M Salo; Jiang Xia; C Anderson Johnson; Yan Li; Edward L Avol; Jie Gong; Stephanie J London
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of epidemiology     Volume:  14     ISSN:  1047-2797     ISO Abbreviation:  Ann Epidemiol     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-07     Completed Date:  2005-04-21     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  9100013     Medline TA:  Ann Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  543-50     Citation Subset:  IM    
National Institute of Environmental Health Sciences, Epidemiology Branch, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA.
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MeSH Terms
Air Pollution, Indoor / adverse effects*
Allergens / classification,  immunology*,  poisoning
Animals, Domestic / immunology
Asthma / epidemiology,  etiology*
China / epidemiology
Cross-Sectional Studies
Grant Support
1 P50 CA94735-02/CA/NCI NIH HHS; Z01 ES 49019/ES/NIEHS NIH HHS
Reg. No./Substance:

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