Document Detail

Indomethacin and recurrent ileal perforations in a preterm infant.
MedLine Citation:
PMID:  8410386     Owner:  NLM     Status:  MEDLINE    
This article reports a case of a very low birth weight infant who was given intravenous indomethacin for a symptomatic patent ductus arteriosus and subsequently had two isolated ileal perforations several days apart. Spontaneous or indomethacin-related ileal perforation appears to constitute a separate clinical and pathologic entity, different from necrotizing enterocolitis, with a benign clinical picture and good prognosis when promptly recognized.
G P Giacoia; K Azubuike; J R Taylor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  13     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    1993 Jul-Aug
Date Detail:
Created Date:  1993-11-04     Completed Date:  1993-11-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  297-9     Citation Subset:  IM    
Department of Pediatrics, University of Oklahoma College of Medicine, Tulsa.
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MeSH Terms
Ductus Arteriosus, Patent / drug therapy
Ileal Diseases / chemically induced*
Indomethacin / adverse effects*,  therapeutic use
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature, Diseases / chemically induced*
Intestinal Perforation / chemically induced*
Reg. No./Substance:

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