| Indomethacin-induced colon perforation in Bartter's syndrome. | |
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MedLine Citation:
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PMID: 19347676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Bartter's syndrome (BS) is an inherited renal tubular disorder characterized by hypokalemia, hypochloremic metabolic alkalosis, and hyperaldosteronism with normal blood pressure. A 22-year-old woman was referred at 23 week of gestation. Polyhydramnios was detected and the chloride level of the amniotic fluid was high. The mother was treated with indomethacin from 26 to 31 week of gestation. The newborn was delivered at 34 week of gestation. At 8th day of life, indomethacin was also started for the baby. After three days, a colonic perforation developed. Indomethacin-induced colon perforation is uncommon in antenatal Bartter's syndrome. This patient indicates that administration of indomethacin in both antenatal and/or early postnatal period may be associated with colonic perforation. |
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Authors:
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Emel Ataoglu; Mahmut Civilibal; Ayse Ayaz Ozkul; Ipek Guney Varal; Elmas Reyhan Oktay; Elevli Murat |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-04-06 |
Journal Detail:
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Title: Indian journal of pediatrics Volume: 76 ISSN: 0973-7693 ISO Abbreviation: Indian J Pediatr Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-04-06 Completed Date: 2009-07-01 Revised Date: 2009-07-15 |
Medline Journal Info:
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Nlm Unique ID: 0417442 Medline TA: Indian J Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 322-3 Citation Subset: IM |
Affiliation:
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Department of Neonatology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amniotic Fluid / chemistry* Anti-Inflammatory Agents, Non-Steroidal / adverse effects* Bartter Syndrome / complications, diagnosis*, drug therapy, genetics Colonic Diseases / complications, genetics Female Gestational Age Humans Indomethacin / adverse effects* Infant, Newborn Intestinal Perforation / chemically induced*, complications, genetics Mutation Polyhydramnios / drug therapy*, genetics Pregnancy Pregnancy Complications / genetics |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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