| Indomethacin in severe twin-to-twin transfusion syndrome. | |
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MedLine Citation:
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PMID: 8442793 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite advances in maternal fetal medicine, the management of severe twin-to-twin transfusion syndrome in the second trimester presents a significant challenge. Presently, there is no uniformly accepted management protocol that is available for the treatment of this syndrome. We report the use of indomethacin in three cases of severe twin-to-twin transfusion syndrome in the second trimester. In the three cases of severe twin-to-twin transfusion syndrome no reduction of amniotic fluid in either sac was demonstrated. Two cases were complicated by single intrauterine fetal death within 72 hours of initiating indomethacin therapy. Because of our experience with these three cases, we conclude that indomethacin does not prevent perinatal mortality in patients with severe twin-to-twin transfusion syndrome. |
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Authors:
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J M Jones; A J Sbarra; L Dilillo; C L Cetrulo; M E D'Alton |
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2637623 - Dandy-walker syndrome: follow up of an unoperated case and her identical twin. 17766613 - First- and second-trimester screening: detection of aneuploidies other than down syndrome. 2637623 - Dandy-walker syndrome: follow up of an unoperated case and her identical twin. |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of perinatology Volume: 10 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 1993 Jan |
Date Detail:
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Created Date: 1993-04-08 Completed Date: 1993-04-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 24-6 Citation Subset: IM |
Affiliation:
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Department of Maternal Fetal Medicine, St. Margaret's Hospital for Women, Boston, Massachusetts. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Fetal Death / prevention & control Fetofetal Transfusion / drug therapy*, mortality Humans Indomethacin / therapeutic use* Infant Mortality Infant, Newborn Pregnancy Pregnancy Trimester, Second |
| Chemical | |
Reg. No./Substance:
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53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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