| Indomethacin and canine lower esophageal sphincter pressure. | |
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MedLine Citation:
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PMID: 879154 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A total of 20 experiments were carried out on 10 dogs to investigate the effect of indomethacin, administered rectally, on the canine lower esophageal sphincter pressure (LESP). Indomethacin increases LESP. Its effect begins 60 minutes after rectal administration and lasts for about 120 minutes. It reaches its highest level 90 minutes after administration. Indomethacin has no effect on the canine fundal or esophageal pressure. |
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Authors:
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R E Mokka; L Punto; M I Kairaluoma; T K Larmi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of gastroenterology Volume: 67 ISSN: 0002-9270 ISO Abbreviation: Am. J. Gastroenterol. Publication Date: 1977 Apr |
Date Detail:
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Created Date: 1977-08-25 Completed Date: 1977-08-25 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0421030 Medline TA: Am J Gastroenterol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 366-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dogs Esophagogastric Junction / drug effects, physiology* Indomethacin / administration & dosage, pharmacology* Pressure Rectum Suppositories |
| Chemical | |
Reg. No./Substance:
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0/Suppositories; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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