Document Detail


Indomethacin by intravenous infusion in ureteral colic. A multicentre study.
MedLine Citation:
PMID:  7163787     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a multicentre study the analgetic effect of indomethacin in ureteral colic was analyzed. Indomethacin, which inhibits the synthesis of prostaglandin, was given by intravenous infusion in a dose of 50 mg. The study comprised 198 patients with 252 attacks of ureteral colic. Satisfactory relief of pain was obtained in 212 attacks (84%). No serious side effects of indomethacin were observed. The pain recurred within four hours in only 15 patients (7%), in 12 of them during a diagnostic intravenous pyelography. The relief of pain may be explained by reduced glomerular filtration pressure and/or diminished urinary excretion, causing rapid fall in the renal pelvic pressure and in the tension of the pelvi-ureteral wall. A low extracellular volume of fluid in a patient with ureteral colic may be essential for analgetic action of indomethacin.
Authors:
J G Sjödin; D Holmlund
Related Documents :
1912857 - Long term renal outcome of childhood haemolytic uraemic syndrome.
17762657 - Pulse pressure is an independent determinant of renal function decline during treatment...
3082107 - Constant glomerular filtration rate in diabetic nephropathy. correlation to blood press...
8567047 - Effects of amlodipine on glomerular filtration, growth, and injury in experimental hype...
8862077 - A comparison of the pathophysiologic effects of carbon dioxide, nitrous oxide, and heli...
18771767 - Predicting changes in knee adduction moment due to load-altering interventions from pre...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  16     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1982  
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  221-5     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Pressure / drug effects
Colic / drug therapy*
Female
Humans
Indomethacin / administration & dosage,  adverse effects,  therapeutic use*
Infusions, Parenteral
Kidney Pelvis / physiopathology
Male
Middle Aged
Pressure
Ureteral Diseases / drug therapy*
Chemical
Reg. No./Substance:
53-86-1/Indomethacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Continence training of children with neurogenic bladder and detrusor hyperactivity: effect of atropi...
Next Document:  Assessment of renal function from plasma urea and plasma creatinine in children.