Document Detail


Individualized total cavopulmonary connection technique for patients with asplenia syndrome.
MedLine Citation:
PMID:  11996270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Outcomes after univentricular repair for patients with asplenia syndrome remain unsatisfactory, not only because of clinical difficulties in patient selection, but also secondary to technical difficulties in the separation of the systemic and pulmonary circulations, particularly with the rerouting technique for the inferior systemic veins. METHODS: Between February 1995 and May 2000, a total of 14 consecutive patients with asplenia syndrome underwent bidirectional cavopulmonary connection with obliteration of additional pulmonary blood flow, followed by a total cavopulmonary connection. The rerouting technique for inferior systemic venous blood flow was individualized to optimize laminar nonturbulent flow characteristics in the pathway, and to minimize prosthetic load and suture load on the atrial wall. The lateral tunnel or tube conduit technique was used in an extraatrial, intra-extraatrial, or intraatrial fashion. No fenestration was applied. RESULTS: No hospital mortality was observed. Systemic venous flow was evaluated using magnetic resonance angiography, revealing no signs of obstruction, turbulence, or stasis either in or near the reconstructed pathways, irrespective of the rerouting technique. Postoperative catheterization revealed favorable hemodynamics including an inferior vena cava pressure of 13 +/- 2 mm Hg and arterial oxygen saturation of 93.4% +/- 3.5% at room air. All patients have remained free of symptoms, although 1 patient died of acute septic complications 3.5 years after the procedure. CONCLUSIONS: The complexity of cardiac anomalies in asplenia syndrome warrants individualization of the total cavopulmonary connection technique used in reconstruction of the inferior systemic venous pathway. Optimizing flow characteristics in the pathway should be a priority. A staging approach allows suitable selection of candidates for univentricular repair.
Authors:
Ryo Aeba; Toshiyuki Katogi; Kenichi Hashizume; Yoshimi Iino; Shiaki Kawada; Yuji Yuasa
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  73     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-05-08     Completed Date:  2002-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1274-80; discussion 1280-1     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiovascular Surgery, Keio University, Tokyo, Japan. aeba@sc.itc.keio.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple*
Adolescent
Child
Child, Preschool
Follow-Up Studies
Heart Bypass, Right / methods*
Heart Defects, Congenital / surgery*
Humans
Infant
Postoperative Complications
Retrospective Studies
Spleen / abnormalities*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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