Document Detail


Individualized developmental care for a large sample of very preterm infants: health, neurobehaviour and neurophysiology.
MedLine Citation:
PMID:  19735497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To assess medical and neurodevelopmental effects of Newborn Individualized Developmental Care and Assessment Program (NIDCAP) for a large sample of very early-born infants. METHODS: One hundred and seven singleton inborn preterm infants, <29 weeks gestational age (GA), <1250 g birth weight, enrolled in three consecutive phases, were randomized within phase to NIDCAP (treatment, E) or standard care (C). Treatment extended from admission to the Newborn Intensive Care Unit to 2 weeks corrected age (wCA). Outcome included medical, neurobehavioural and neurophysiological status at 2 wCA, and growth and neurobehavioural status at 9 months (m) CA. RESULTS: The C- and E-group within each of the three consecutive phases and across the three phases were comparable in terms of all background measures; they therefore were treated as one sample. The results indicated for the E-group significant reduction in major medical morbidities of prematurity as well as significantly improved neurodevelopmental (behaviour and electrophysiology) functioning at 2 wCA; significantly better neurobehavioural functioning was also found at 9 mCA. CONCLUSION: The NIDCAP is an effective treatment for very early-born infants. It reduces health morbidities and enhances neurodevelopment, functional competence and life quality for preterm infants at 2 w and 9 mCA.
Authors:
G McAnulty; F H Duffy; S Butler; R Parad; S Ringer; D Zurakowski; H Als
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2009-09-07
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  98     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-01-06     Completed Date:  2010-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1920-6     Citation Subset:  IM    
Affiliation:
Department of Psychiatry (Psychology), Children's Hospital Boston and Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Child Development / physiology*
Female
Gestational Age
Health Status
Humans
Infant Care / methods*
Infant, Newborn
Infant, Premature / growth & development*
Infant, Very Low Birth Weight / growth & development*
Intensive Care, Neonatal / methods*
Male
Neurophysiology
Neuropsychology
Patient Care Planning*
Program Evaluation
Treatment Outcome
Grant Support
ID/Acronym/Agency:
P30HD18655/HD/NICHD NIH HHS; R01HD3826/HD/NICHD NIH HHS

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