Document Detail

Individualised homeopathy as an adjunct in the treatment of childhood asthma: a randomised placebo controlled trial.
MedLine Citation:
PMID:  12668794     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Homeopathy is frequently used to treat asthma in children. In the common classical form of homeopathy, prescriptions are individualised for each patient. There has been no rigorous investigation into this form of treatment for asthma. METHODS: In a randomised, double blind, placebo controlled trial the effects of individualised homeopathic remedies were compared with placebo medication in 96 children with mild to moderate asthma as an adjunct to conventional treatment. The main outcome measure was the active quality of living subscale of the Childhood Asthma Questionnaire administered at baseline and follow up at 12 months. Other outcome measures included other subscales of the same questionnaire, peak flow rates, use of medication, symptom scores, days off school, asthma events, global assessment of change, and adverse reactions. RESULTS: There were no clinically relevant or statistically significant changes in the active quality of life score. Other subscales, notably those measuring severity, indicated relative improvements but the sizes of the effects were small. There were no differences between the groups for other measures. CONCLUSIONS: This study provides no evidence that adjunctive homeopathic remedies, as prescribed by experienced homeopathic practitioners, are superior to placebo in improving the quality of life of children with mild to moderate asthma in addition to conventional treatment in primary care.
A White; P Slade; C Hunt; A Hart; E Ernst
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Thorax     Volume:  58     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-01     Completed Date:  2003-05-05     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  England    
Other Details:
Languages:  eng     Pagination:  317-21     Citation Subset:  IM    
Complementary Medicine, Peninsula Medical School, University of Exeter, Exeter EX2 4NT, UK.
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MeSH Terms
Administration, Inhalation
Anti-Asthmatic Agents / administration & dosage
Asthma / drug therapy*
Double-Blind Method
Materia Medica / therapeutic use*
Quality of Life
Treatment Outcome
Reg. No./Substance:
0/Anti-Asthmatic Agents; 0/Materia Medica
Comment In:
Thorax. 2003 Sep;58(9):827; author reply 828   [PMID:  14510008 ]
Thorax. 2003 Sep;58(9):826-7; author reply 828   [PMID:  14510007 ]
Thorax. 2003 Sep;58(9):826; author reply 828   [PMID:  14510006 ]
Thorax. 2003 Sep;58(9):826; author reply 828   [PMID:  12947153 ]
Thorax. 2003 Sep;58(9):827-8; author reply 828   [PMID:  14510009 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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