Document Detail


Individual differences in reward drive predict neural responses to images of food.
MedLine Citation:
PMID:  16687507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A network of interconnected brain regions, including orbitofrontal, ventral striatal, amygdala, and midbrain areas, has been widely implicated in a number of aspects of food reward. However, in humans, sensitivity to reward can vary significantly from one person to the next. Individuals high in this trait experience more frequent and intense food cravings and are more likely to be overweight or develop eating disorders associated with excessive food intake. Using functional magnetic resonance imaging, we report that individual variation in trait reward sensitivity (as measured by the Behavioral Activation Scale) is highly correlated with activation to images of appetizing foods (e.g., chocolate cake, pizza) in a fronto-striatal-amygdala-midbrain network. Our findings demonstrate that there is considerable personality-linked variability in the neural response to food cues in healthy participants and provide important insight into the neurobiological factors underlying vulnerability to certain eating problems (e.g., hyperphagic obesity).
Authors:
John D Beaver; Andrew D Lawrence; Jenneke van Ditzhuijzen; Matt H Davis; Andrew Woods; Andrew J Calder
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  26     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-11     Completed Date:  2006-05-31     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5160-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / physiology*
Cues
Evoked Potentials, Visual / physiology*
Female
Food*
Humans
Magnetic Resonance Imaging
Male
Nerve Net / physiology*
Reward*
Visual Perception / physiology*
Grant Support
ID/Acronym/Agency:
G0001237//Medical Research Council; MC_U105579214//Medical Research Council; MC_U105580446//Medical Research Council
Comments/Corrections
Comment In:
J Neurosci. 2006 Jul 26;26(30):7775-6   [PMID:  16871685 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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