Document Detail

Indirect measurement of aneurysm wall thickness using digital stethoscope.
MedLine Citation:
PMID:  19660238     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: No existing in vivo technique can measure aneurysm wall thickness for evaluation of rupture risk. Intracranial aneurysms produce bruits at a special range of frequency that are highly influenced by the wall thickness. Understanding of the mechanism that generates bruits may allow us to learn aneurysm behavior non-invasively. METHODS: A new theory was proposed to account for an interaction between an aneurysm and its parent vessel. Four patients with ophthalmic aneurysms were studied with a digital electronic stethoscope before and after endovascular treatment. Energy spectra of bruits were obtained from digital recording at both eyes. Change of energy spectra was used as an objective indication for aneurysm bruits. Additional four cases were obtained from a previous report. RESULTS: Aneurysm bruits are affected by both aneurysm size and wall thickness. These sounds disappear after coil embolization and parent artery occlusion, but not by stenting. Both large and small aneurysms generate sounds at high frequency. Aneurysms at 6 mm produced very low frequency sound. Wall thickness decreases with aneurysm size, and the decrease is more pronounced at 8 mm. CONCLUSIONS: Interaction between an intracranial aneurysm and its parent vessel is important in interpretation of aneurysm bruits. An analysis of in vivo measurements shows a rapid decline in wall thickness for 8 mm aneurysms.
Liang-Der Jou; Michel E Mawad
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-08-05
Journal Detail:
Title:  Neurological research     Volume:  32     ISSN:  1743-1328     ISO Abbreviation:  Neurol. Res.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-28     Completed Date:  2010-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  661-5     Citation Subset:  IM    
Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA.
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MeSH Terms
Embolization, Therapeutic / methods
Follow-Up Studies
Functional Laterality
Intracranial Aneurysm / diagnosis*,  surgery
Middle Aged
Signal Processing, Computer-Assisted*
Spectrum Analysis / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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