Document Detail

Indinavir-associated toxicity mimicking urinary tuberculosis in a patient with AIDS.
MedLine Citation:
PMID:  18553024     Owner:  NLM     Status:  MEDLINE    
This case reported to a patient with AIDS who presented persistent sterile leukocyturia and hematuria, lower back pain, bladder suffering symptoms, and renal papillary necrosis which were thought to be secondary to urinary tuberculosis but were demonstrated to be indinavir-associated side effects. The intention of this report is to remind medical professionals involved in the care of HIV+ patients of this possible association in order to avoid unnecessary investigation and to stress the need of careful periodical assessment of renal function and urinalysis in patients treated with indinavir.
Vinicius Daher Alvares Delfino; Natally Marques Santiago; Altair Jacob Mocelin; Luiz Fernando Kunii; André Luiz Bortoliero
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases     Volume:  12     ISSN:  1678-4391     ISO Abbreviation:  Braz J Infect Dis     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-06-16     Completed Date:  2009-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812937     Medline TA:  Braz J Infect Dis     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  99-100     Citation Subset:  IM    
Nephrology Department, State University of Londrina, Londrina, PR, Brazil.
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MeSH Terms
Acquired Immunodeficiency Syndrome / drug therapy*
Diagnosis, Differential
Glomerular Filtration Rate
HIV Protease Inhibitors / adverse effects*
Indinavir / adverse effects*
Kidney Papillary Necrosis / chemically induced*,  diagnosis*
Middle Aged
Tuberculosis, Urogenital / diagnosis*
Reg. No./Substance:
0/HIV Protease Inhibitors; 150378-17-9/Indinavir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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