| Indices of copper status in humans consuming a typical American diet containing either fructose or starch. | |
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MedLine Citation:
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PMID: 4025196 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-four male subjects originally participated in a study to determine the effects of feeding diets comparatively low in copper (1.03 mg/day/2850 kcal) and containing either 20% fructose or starch on indices of copper status. During the course of feeding the diets for 11 wk, four of the subjects exhibited heart-related abnormalities and were removed from the study. Fructose ingestion had no effect on serum ceruloplasmin activity or serum copper concentration but did significantly reduce cuprozinc superoxide dismutase (SOD) activity of erythrocytes as compared to starch. Repletion of the subjects with 3 mg copper/day for 3 wk significantly increased SOD levels in subjects previously fed fructose but not starch. Apparent copper balance was significantly greater when the subjects consumed the fructose as compared to the starch diet. These results suggest that the type of dietary carbohydrate fed can differentially affect indices of copper status in humans. |
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Authors:
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S Reiser; J C Smith; W Mertz; J T Holbrook; D J Scholfield; A S Powell; W K Canfield; J J Canary |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 42 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1985-09-05 Completed Date: 1985-09-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 242-51 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ceruloplasmin / blood Copper / blood* Dietary Carbohydrates / pharmacology* Energy Intake Food Habits Fructose / pharmacology* Humans Male Middle Aged Starch / pharmacology* Superoxide Dismutase / blood United States / ethnology |
| Chemical | |
Reg. No./Substance:
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0/Dietary Carbohydrates; 30237-26-4/Fructose; 7440-50-8/Copper; 9005-25-8/Starch; EC 1.15.1.1/Superoxide Dismutase; EC 1.16.3.1/Ceruloplasmin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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