Document Detail

Indication for using extracorporeal membrane oxygenation in congenital diaphragmatic hernias and pulmonary hypoplasia.
MedLine Citation:
PMID:  1610756     Owner:  NLM     Status:  MEDLINE    
Despite the apparent surgical simplicity of the anatomic defect, congenital diaphragmatic hernia continues to be a critical problem in neonatal surgery, so that survival is still uncertain. Therefore, we must realize that the barriers to survival are pulmonary parenchymal and vascular hypoplasia as well as the complex syndrome of persisting fetal circulation. However, new treatment methods, such as extracorporeal membrane oxygenation (ECMO), although controversial, may improve survival. We believe that no infant should be excluded from diaphragmatic repair or consideration for ECMO-support before accurate predictive parameters have been developed that take both pulmonary hypoplasia and pulmonary hypertension into account. ECMO additionally enables us to postpone the operation until stabilization of the newborn (Late Operation Protocol). Apart from this, we can probably improve the long-term results after ECMO by reconstructing the common carotid artery.
W Brands; W Kachel; H Wirth; I Joppich; P Lasch; V Varnholt
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie     Volume:  2     ISSN:  0939-7248     ISO Abbreviation:  Eur J Pediatr Surg     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-07-24     Completed Date:  1992-07-24     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9105263     Medline TA:  Eur J Pediatr Surg     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  81-6     Citation Subset:  IM    
Kinderchirurgische Universitätsklinik Mannheim.
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MeSH Terms
Combined Modality Therapy
Critical Care / methods
Extracorporeal Membrane Oxygenation*
Follow-Up Studies
Hernia, Diaphragmatic / congenital*,  mortality,  therapy
Infant, Newborn
Lung / abnormalities*
Respiratory Distress Syndrome, Newborn / mortality,  therapy*
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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