Document Detail


Indian childhood-like cirrhosis in three Saudi Arabian siblings.
MedLine Citation:
PMID:  10824216     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three Saudi siblings, two girls and one boy, presented at the ages of 7, 6 and 2.5 years, respectively, and were diagnosed as having features of Indian childhood cirrhosis (ICC). The two girls presented at a late stage of the disease and the boy was diagnosed during routine examination of the family. The initial presenting complaint was abdominal distention and pruritus. All three had a rapid and fatal course. There was no evidence of increased copper ingestion by the families, supporting the suggestion of a hereditary metabolic role in the aetiology of ICC. As far as we are aware, this is the first report of ICC in Saudi Arabian children.
Authors:
P O Abiodun; A A Albarki; M Dewan; S H Annobil
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of tropical paediatrics     Volume:  20     ISSN:  0272-4936     ISO Abbreviation:  Ann Trop Paediatr     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-06-14     Completed Date:  2000-06-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8210625     Medline TA:  Ann Trop Paediatr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  61-6     Citation Subset:  IM    
Affiliation:
Department of Child Health, Asir Central Hospital, Abha, Kingdom of Saudi Arabia. yeleabi@gto.net.om
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Consanguinity
Fatal Outcome
Female
Humans
Liver Cirrhosis / complications,  genetics*
Male
Nuclear Family
Pruritus / etiology
Saudi Arabia

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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