Document Detail

Independent predictors of complication following surgery for spinal metastasis.
MedLine Citation:
PMID:  23392558     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Surgery for spinal metastasis is often associated with significant morbidity. Despite a number of preoperative scoring systems/scales and identified variables that have been reported to predict complication risk, clinical studies that directly evaluate this issue using multivariate analysis are scarce. The goal of our study was to assess independent predictors of complication after surgery for spinal metastasis.
METHODS: We queried electronic medical records to identify a consecutive population of adult patients who underwent surgery for spinal metastasis for the period June 2005 through June 2011. Utilizing multivariate logistic regression, we assessed independent predictors of perioperative and postoperative adverse events.
RESULTS: A total of 106 patients were included in the final analysis. Overall complication rate was 21.7 %. Independent predictors for higher rates of complication were age greater than 40 years [40-65 years had odds ratio (OR) 1.91, 95 % confidence interval (CI) 1.02-16.78 and >65 years had OR 5.17, 95 % CI 1.54-29.81] and metastatic lesions involving three or more contiguous levels of the spine (OR 2.76, 95 % CI 1.09-9.61).
CONCLUSIONS: Patients older than 40 years or patients who have metastatic lesions involving three or more contiguous vertebral levels appear to be at higher risk for complication. Patients older than 65 years have the greatest likelihood of complication.
Darryl Lau; Matthew R Leach; Khoi D Than; John Ziewacz; Frank La Marca; Paul Park
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Publication Detail:
Type:  Journal Article     Date:  2013-02-08
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  22     ISSN:  1432-0932     ISO Abbreviation:  Eur Spine J     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-06-10     Completed Date:  2014-01-07     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1402-7     Citation Subset:  IM    
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MeSH Terms
Age Distribution
Age Factors
Logistic Models
Middle Aged
Odds Ratio
Orthopedic Procedures
Postoperative Complications / epidemiology*
Retrospective Studies
Risk Factors
Spinal Neoplasms / secondary*,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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