Document Detail


Indapamide and bendrofluazide: a comparison in the management of essential hypertension.
MedLine Citation:
PMID:  7041937     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension. 2 Indapamide (2.5 mg a day) and bendrofluazide (5 mg a day) produced a significant but equivalent fall in blood pressure. 3 Both drugs caused a reduction in body weight and serum potassium with a rise in plasma renin activity but there were no other major side effects. 4 In twelve patients treated with a combination of indapamide and bendrofluazide there was no additional fall in mean blood pressure or serum potassium compared to treatment with bendrofluazide or indapamide alone.
Authors:
R F Bing; G I Russell; J D Swales; H Thurston
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Publication Detail:
Type:  Case Reports; Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of clinical pharmacology     Volume:  12     ISSN:  0306-5251     ISO Abbreviation:  Br J Clin Pharmacol     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-07-08     Completed Date:  1982-07-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503323     Medline TA:  Br J Clin Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  883-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Bendroflumethiazide / therapeutic use*
Blood Pressure / drug effects
Body Weight / drug effects
Diuretics / therapeutic use*
Electrolytes / blood
Female
Humans
Hypertension / drug therapy*
Indapamide / therapeutic use*
Male
Middle Aged
Renin / blood
Time Factors
Urea / blood
Chemical
Reg. No./Substance:
0/Diuretics; 0/Electrolytes; 26807-65-8/Indapamide; 57-13-6/Urea; 73-48-3/Bendroflumethiazide; EC 3.4.23.15/Renin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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