| Incremental shuttle walk test in the assessment of patients for heart transplantation. | |
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MedLine Citation:
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PMID: 11454837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the incremental shuttle walk test (ISWT) with treadmill exercise testing (TT) derived measurement of peak oxygen consumption (peak VO(2)) in patients undergoing assessment for cardiac transplantation. DESIGN: Prospective comparison. All investigations occurred during a single period of admission for transplant assessment. SETTING: Single UK cardiothoracic transplantation unit. PATIENTS: 25 patients recruited (21 men). Mean age was 53 years. INTERVENTIONS: Patients underwent two TT of peak VO(2) using the modified Naughton protocol and three (one practice) ISWT. Investigations were performed on consecutive days. MAIN OUTCOME MEASURES: Main outcome measures were repeatability of TT and ISWT assessments; relation between peak VO(2) and distance walked in the ISWT; and receiver operating characteristic (ROC) analysis to establish a distance walked in the ISWT that predicted which patients would have a peak VO(2) greater than 14 ml/min/kg. RESULTS: Both the ISWT and the TT were highly reproducible. Following the first practice walk, mean (SD) ISWT distances were 400.0 (146) m (ISWT2) and 401.3 (129) m (ISWT3), r = 0.90, p < 0.0001. Mean peak VO(2) by TT was 15.2 (4.4) ml/kg/min (TT1) and 15.0 (4.4) ml/kg/min (TT2), r = 0.83, p < 0.0001. The results revealed a strong correlation between distance covered in the ISWT and peak VO(2) obtained during TT (r = 0.73, p = 0.0001). ROC analysis showed that a distance walked of 450 m allowed the selection of patients with a peak VO(2) of over 14 ml/min/kg. CONCLUSIONS: This work confirms the utility of the ISWT in the assessment of exercise capacity in patients with severe heart failure undergoing assessment for cardiac transplantation. ISWT may provide a widely applicable surrogate measure for peak VO(2) estimation in this population. Shuttle distance walked may therefore allow the convenient, serial assessment of patients with heart failure before referral for transplantation. |
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Authors:
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M E Lewis; C Newall; J N Townend; S L Hill; R S Bonser |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Heart (British Cardiac Society) Volume: 86 ISSN: 1468-201X ISO Abbreviation: Heart Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-07-16 Completed Date: 2001-08-09 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9602087 Medline TA: Heart Country: England |
Other Details:
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Languages: eng Pagination: 183-7 Citation Subset: AIM; IM |
Affiliation:
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Heart and Lung Transplantation Unit, Department of Cardiothoracic Surgery, Queen Elizabeth Hospital, University Hospital NHS Trust, Birmingham B15 2TH, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Exercise Test
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methods* Female Heart Diseases / physiopathology, surgery Heart Transplantation / methods* Humans Male Middle Aged Oxygen Consumption / physiology* Patient Selection* Prospective Studies Reproducibility of Results Sensitivity and Specificity Walking / physiology |
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