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Increasing use of radioiodine in young people with thyrotoxicosis in Great Britain.
MedLine Citation:
PMID:  22956555     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ObjectiveRadioiodine (RI) is an important therapeutic option in young patients with thyrotoxicosis. We wanted to determine whether RI is being used more frequently in this age group.DesignNational survey of Great Britain (England, Wales and Scotland).MethodsSixty-one medical physics departments were asked to provide the age and number of patients with thyrotoxicosis <21 years treated with RI (1990-2008). Information on the total number of RI treatments for thyrotoxicosis was also collected.Results43 departments (70%), with representation from 21 of the 25 most populous areas of Great Britain provided data on 69258 treatments. The number of treatments recorded on patients <21 years of age during this period was 560 (0.9%). The frequency of treatments in young people as a percentage of the total increased from 0.2% in 1990 to 1.5% in 2008 (p<0.001). When the 18 centres submitting at least 17 years data were analysed, a similar pattern was observed. The maximum number of young people treated was greatest in 2008 (62) with a fall in the youngest age at which RI was administered from 18 years (1990) to 11 years (2008).ConclusionsA rising proportion of patients with thyrotoxicosis receiving RI are <21 years of age. This is largely due to an increase in the number of young people treated with a reduction in the minimum age at RI administration. We suspect that European clinicians are becoming more comfortable with RI treatment in young people with thyrotoxicosis although a changing incidence is a potential contributing factor.
Authors:
Neil Turner; Ian Driver; Jane Salotti; Mark Pearce; Tim David Cheetham
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-6
Journal Detail:
Title:  European journal of endocrinology / European Federation of Endocrine Societies     Volume:  -     ISSN:  1479-683X     ISO Abbreviation:  Eur. J. Endocrinol.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423848     Medline TA:  Eur J Endocrinol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
N Turner, Regional Medical Physics Department, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.
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