Document Detail

Increasing the sensitivity of caries clinical trials by applying logistic modelling to specific teeth.
MedLine Citation:
PMID:  3902345     Owner:  NLM     Status:  MEDLINE    
An alternative statistical approach is proposed for analysing data from longitudinal clinical trials. Caries increments on those teeth which are known to be particularly susceptible to caries for the population under study are represented by a linear logistic probability model. Expression of the caries increments in the form of a probability model should lead to a better understanding of the relative importance of the various factors which contribute to the caries increment in the population under study. When this model was applied to caries increments on the permanent second molars of children aged 11-13 yr at the baseline of two 3-yr trials, the sensitivity of statistical analysis was up to five times greater than that obtained with traditional statistical methods.
E Huntington
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Community dentistry and oral epidemiology     Volume:  13     ISSN:  0301-5661     ISO Abbreviation:  Community Dent Oral Epidemiol     Publication Date:  1985 Oct 
Date Detail:
Created Date:  1985-12-18     Completed Date:  1985-12-18     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  0410263     Medline TA:  Community Dent Oral Epidemiol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  264-7     Citation Subset:  D; IM    
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MeSH Terms
Clinical Trials as Topic
DMF Index
Dental Caries / prevention & control*
Models, Biological*
Time Factors
Tooth Eruption

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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