Document Detail


Increasing resistance to penicillin in Streptococcus pneumoniae in southern Sweden.
MedLine Citation:
PMID:  7939430     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The susceptibility to penicillin of 6 prevalent pneumococcal types isolated from nasopharynx in 1992 was compared with that of corresponding types from 1980-82. The 6 types or groups, 6, 9, 14, 15, 19 and 23, constituted 78% of consecutive isolates. 19/204 isolates in 1992 were intermediately resistant (MIC 0.12-1.0 mg/l) in comparison with 1/194 from 1980-82 (p < 0.001). Resistant strains (MIC > or = 2 mg/l) were not found. Of group 15, no fewer than 10/31 isolates were intermediately resistant, which may support the clonal origin and spread of penicillin-resistant pneumococci. At least 5.0% of nasopharyngeal isolates are now intermediately resistant to penicillin. This figure is substantially higher than the 2% earlier reported in Sweden.
Authors:
K Ekdahl; C Kamme
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  26     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  1994  
Date Detail:
Created Date:  1994-11-22     Completed Date:  1994-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  301-5     Citation Subset:  IM    
Affiliation:
Department of Infectious Diseases, Lund University Hospital, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Child, Preschool
Humans
Infant
Microbial Sensitivity Tests
Middle Aged
Nasopharynx / microbiology
Penicillin G / pharmacology
Penicillin Resistance*
Penicillin V / pharmacology
Reproducibility of Results
Streptococcus pneumoniae / drug effects*,  isolation & purification
Sweden
Time Factors
Chemical
Reg. No./Substance:
61-33-6/Penicillin G; 87-08-1/Penicillin V

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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