Document Detail

Increasing pre-excitation during exercise and isoproterenol infusion. Evidence for a catecholamine sensitive bypass tract.
MedLine Citation:
PMID:  469445     Owner:  NLM     Status:  MEDLINE    
A patient with atypical chest pain developed pre-excitation during exercise and isoproterenol infusion, with "ischemic" ST depression only during the pre-excited beats. Coronary angiography and myocardial lactate extraction showed no evidence of abnormal coronary vessels. Electrophysiologic study and pacing-induced tachycardia did not induce pre-excitation, whereas exercise induced progressive increase in pre-excitation. The data are consistent with an unusual form of pre-excitation, perhaps related to responsiveness of an accessory bypass tract to catecholamine stimulation. The data also show that the false positive exercise test in this syndrome is due to progressively increasing pre-excitation and therefore more abnormal repolarization.
G M Weisfogel; R A Stein; A Fernaine; N Krasnow
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  12     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-10-24     Completed Date:  1979-10-24     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology,  physiopathology*
Catecholamines / physiology*
Exercise Test
Heart Catheterization
Heart Conduction System / physiopathology*
Isoproterenol / adverse effects*
Physical Exertion*
Reg. No./Substance:
0/Catecholamines; 7683-59-2/Isoproterenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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