Document Detail


Increasing physical education in high school students: effects on concentration of circulating endothelial progenitor cells.
MedLine Citation:
PMID:  18677165     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: Levels of endothelial progenitor cells (EPCs), that can be increased by regular exercise, correlate with vascular function. In the context of primary prevention, the impact of regular physical activity on the amount and function of EPC has not yet been investigated in school children. METHODS: Four sixth grade classes of high school students (n=92) were randomly assigned to either the intervention group (IG) with daily physical exercise (45 min) at school or to the control group (CG) with conventional physical education (PE) (2 h/week). In addition, one sixth grade class at a high school focused on competitive sports (PE) served as a reference group. After 1 school year, exercise capacity and the amount and function of EPCs were evaluated. RESULTS: After 1 year, a significantly higher Vo2max was evident in the intervention group. Nevertheless, exercise capacity did not reach the level of children from PE. In addition, exercise intervention was successful in increasing the amount of EPCs but failed to increase the migratory capacity of the cells. CONCLUSION: The result of this study shows, that intensified, supervised school sports leads to an increase in exercise capacity and EPCs in children. Nevertheless, its effect on primary prevention in cardiovascular disease has to be proven in further longitudinal studies.
Authors:
Claudia Walther; Volker Adams; Inga Bothur; Kati Drechsler; Sven Fikenzer; Melanie Sonnabend; Beatrice Bublitz; Antje Körner; Sandra Erbs; Martin Busse; Gerhard Schuler
Related Documents :
23154995 - The effect of hypoxemia and exercise on acute mountain sickness symptoms.
964285 - Exercise performance in children and adolescents after surgical repair of tetralogy of ...
12578245 - An assessment of the validity and reliability of two perceived exertion rating scales a...
1310835 - Wheat-dependent exercise-induced anaphylaxis: inhibition by sodium bicarbonate.
24251745 - Effects of regular aerobic exercise on post-exercise vagal reactivation in young female.
22878275 - Corrected end-tidal p(co(2)) accurately estimates pa(co(2)) at rest and during exercise...
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology     Volume:  15     ISSN:  1741-8267     ISO Abbreviation:  Eur J Cardiovasc Prev Rehabil     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-04     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101192000     Medline TA:  Eur J Cardiovasc Prev Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  416-22     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Heart Center, University of Leipzig, Leipzig, Germany. waltherc@medizin.uni-leipzig.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antigens, CD34 / analysis
Cardiovascular Diseases / prevention & control
Cell Count
Cell Movement
Child
Endothelial Cells / cytology*,  physiology
Exercise*
Exercise Tolerance
Female
Humans
Male
Physical Education and Training*
Primary Prevention
Stem Cells / cytology*,  physiology
Chemical
Reg. No./Substance:
0/Antigens, CD34

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evaluation of a recalibrated Systematic Coronary Risk Evaluation cardiovascular risk chart: results ...
Next Document:  Comparative prognostic value of glomerular filtration rate estimating formulas in ischaemic heart di...