| Increasing incidence of Kaposi's sarcoma in black South Africans in KwaZulu-Natal, South Africa (1983-2006). | |
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MedLine Citation:
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PMID: 19625587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to describe the temporal trends in the incidence of Kaposi's sarcoma (KS) in black South Africans in KwaZulu-Natal (KZN). The study was designed as a retrospective record review. The incidence of Kaposi's sarcoma was estimated using administrative records for patients receiving care for KS through public sector oncology clinics in KZN, 1983-2006. Annual age-standardized incidence rates were calculated using provincial census data for the denominator. Age-specific rates were calculated for the pre-AIDS (1983-1989) and for the generalized AIDS epidemic eras (2006). Age-standardized incidence of KS increased in KZN from <1:100,000 in 1990 to at least 15:100,000 in 2006; this increase was observed in both men and women. There was a shift in the peak age-specific incidence rates from the sixth decade of life in the pre-AIDS era to the fourth and fifth decades in the AIDS era. In conclusion, KS is a growing public health problem in KZN, South Africa. These data reinforce the need for comprehensive national access to and roll-out of antiretroviral drugs, given their success in prevention and treatment of KS in first-world settings. |
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Authors:
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A Mosam; H Carrara; F Shaik; T Uldrick; A Berkman; J Aboobaker; H M Coovadia |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of STD & AIDS Volume: 20 ISSN: 0956-4624 ISO Abbreviation: Int J STD AIDS Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-07-23 Completed Date: 2009-11-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9007917 Medline TA: Int J STD AIDS Country: England |
Other Details:
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Languages: eng Pagination: 553-6 Citation Subset: IM; X |
Affiliation:
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Department of Dermatology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal. mosama@ukzn.ac.za |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Continental Ancestry Group* Aged Female Humans Incidence Male Middle Aged Retrospective Studies Sarcoma, Kaposi / drug therapy, epidemiology*, ethnology* South Africa / epidemiology Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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D43TW00231/TW/FIC NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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