| Increasing and supporting the participation of persons of color living with HIV/AIDS in AIDS clinical trials. | |
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MedLine Citation:
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PMID: 20737252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Persons living with HIV/AIDS (PLHA) of color are under-represented in AIDS clinical trials (ACTs), which may limit the generalizability of research findings and denies many individuals access to high levels of care and new treatments available through ACTs. Disproportionately low rates of recruitment in health care settings and by providers are a major barrier to ACTs for this group. Moreover, PLHA of color are more likely than their white peers to decline to participate, mainly due to fear and mistrust (although willingness is also high), negative social norms about ACTs, and difficulty navigating the unfamiliar ACT system. We describe a small number of successful behavioral and structural interventions to increase the participation of PLHA of color in screening for and enrollment into ACTs. HIV care settings, clinical trials sites, and trial sponsors are uniquely positioned to develop procedures, supports, and trials to increase the proportion of PLHA of color in ACTs. |
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Authors:
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Marya Viorst Gwadz; Pablo Colon; Amanda S Ritchie; Noelle R Leonard; Charles M Cleland; Marion Riedel; DeShannon Bowens; Angela D Banfield; Patricia Chang; Robert Quiles; Donna Mildvan |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Current HIV/AIDS reports Volume: 7 ISSN: 1548-3576 ISO Abbreviation: Curr HIV/AIDS Rep Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101235661 Medline TA: Curr HIV/AIDS Rep Country: United States |
Other Details:
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Languages: eng Pagination: 194-200 Citation Subset: IM |
Affiliation:
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New York University College of Nursing, 726 Broadway, New York, NY 10003, USA. marya.gwadz@nyu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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drug therapy,
ethnology African Americans* Clinical Trials as Topic* Ethnic Groups HIV Infections / drug therapy, ethnology*, prevention & control Health Knowledge, Attitudes, Practice Health Services Accessibility Healthcare Disparities / ethnology Hispanic Americans* Humans Intervention Studies Minority Groups Minority Health Patient Compliance Patient Participation Patient Selection* Refusal to Participate / ethnology Trust |
| Grant Support | |
ID/Acronym/Agency:
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1 R01 AI070005/AI/NIAID NIH HHS; P30DA011041/DA/NIDA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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