Document Detail

Increased xanthine oxidase during labour--implications for oxidative stress.
MedLine Citation:
PMID:  9364609     Owner:  NLM     Status:  MEDLINE    
Xanthine dehydrogenase/oxidase (XDH/XO) produces uric acid. When in the oxidase form, this production is coupled with the generation of free radicals. Hypoxia-reperfusion enhances conversion of XDH to XO. Since the placenta is exposed to short periods of hypoxia reperfusion during labour, 17 placentae of pregnancy terminated by elective caesarean section and five placentae of pregnancies terminated by caesarean section during labour were examined for XDH/XO activity. It was found that XO activity was higher in the placentae of labouring women (P = 0.003), which suggests that labour enhances conversion of XDH to XO, facilitating free radical production.
A Many; J M Roberts
Related Documents :
2317469 - Listeriosis revisited: the role of the obstetrician.
10796239 - Cardiotocography for antepartum fetal assessment.
17208929 - The effects of oxygen concentration on in vitro output of prostaglandin e2 and interleu...
10195739 - Region and labour-dependent synthesis of prostaglandin e2 by human fetal membranes.
7820319 - Management of post-term pregnancy: to induce or not?
12118529 - Successful pregnancy in a woman with mut- methylmalonic acidaemia.
18515519 - Bone metabolism in pregnant women exposed to single compared with multiple courses of c...
9314809 - Is incarceration during pregnancy associated with infant birthweight?
2777129 - Premature rupture of the fetal membranes, the phases of the moon and barometer readings.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Placenta     Volume:  18     ISSN:  0143-4004     ISO Abbreviation:  Placenta     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1997-12-11     Completed Date:  1997-12-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  725-6     Citation Subset:  IM    
Magee Womens Research Institute, University of Pittsburgh, Pennsylvania, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cesarean Section
Labor, Obstetric / physiology*
Oxidative Stress / physiology
Placenta / enzymology*
Xanthine Dehydrogenase / metabolism
Xanthine Oxidase / metabolism*
Grant Support
Reg. No./Substance:
EC Dehydrogenase; EC Oxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The interleukin-1 system in gestational tissues at term: effect of labour.
Next Document:  The brain as a symbol-processing machine.