| Increased uptake of 99Tcm-ethyl cysteinate dimer in patients with brain tumours. | |
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MedLine Citation:
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PMID: 11388567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We performed 229 99Tcm-ethyl cysteinate dimer (ECD) single photon emission tomography (SPET) studies in 185 patients with brain tumour. Increased uptake of the tracer was observed in 11 cases. In six of these 11 patients, focal intense activity was seen in the area surrounding the tumour. Five of these six patients had episodes of seizure, and ictal SPET showed further increased uptake in the area of hyperperfusion in one patient. Hyperperfusion surrounding the tumour might be related to seizure. In the remaining five patients, increased accumulation was seen in the tumour. Three of these five patients had a discrepancy between 99Tcm-ECD SPET and 201Tl SPET imaging. There could be some difference in the mechanism of accumulation in the tumour between 99Tcm-ECD and 201Tl. |
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Authors:
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Y Ogawa; R Hashmi; A Aziz; M Ochi; K Hayashi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 22 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-06-04 Completed Date: 2001-11-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 479-83 Citation Subset: IM |
Affiliation:
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Department of Radiology, Nagasaki University School of Medicine, Sakamoto, Japan. yoogawa@net.nagasaki-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Astrocytoma / radionuclide imaging, surgery Brain / metabolism, radionuclide imaging Brain Neoplasms / metabolism, radionuclide imaging*, secondary, surgery Cysteine / analogs & derivatives, diagnostic use, pharmacokinetics* Female Glioblastoma / radionuclide imaging Humans Infant Male Meningioma / radionuclide imaging, surgery Middle Aged Neoplasm Recurrence, Local / radionuclide imaging Oligodendroglioma / radionuclide imaging, surgery Organotechnetium Compounds / diagnostic use, pharmacokinetics* Radiopharmaceuticals / diagnostic use, pharmacokinetics* Tomography, Emission-Computed, Single-Photon* |
| Chemical | |
Reg. No./Substance:
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0/Organotechnetium Compounds; 0/Radiopharmaceuticals; 0/technetium Tc 99m bicisate; 52-90-4/Cysteine |
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