Document Detail


Increased sympathetic nerve activity at home in young subjects with hypertension.
MedLine Citation:
PMID:  2743599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma and urine norepinephrine, epinephrine, plasma renin activity and aldosterone were measured in 11 young men (mean age, 21 years) with a high blood pressure in the clinic who maintained a high home blood pressure and 12 men with an elevated clinic blood pressure who had a normal home blood pressure. Plasma samples were drawn following 30 min rest in the clinic, and 24-hour urine samples were collected at home. The two groups of hypertensives could not be distinguished on the basis of clinic blood pressure, plasma norepinephrine, epinephrine, renin activity or aldosterone. Patients with a high home blood pressure were characterized by a high urinary norepinephrine excretion. These results suggest that the patients whose blood pressure remained elevated at home had an increased sympathetic nerve activity at home.
Authors:
I Saito; S Itsuji; E Takeshita; T Takenaka; T Furukawa; T Saruta; S Nagano; T Sekihara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental hypertension. Part A, Theory and practice     Volume:  11 Suppl 1     ISSN:  0730-0077     ISO Abbreviation:  Clin Exp Hypertens A     Publication Date:  1989  
Date Detail:
Created Date:  1989-08-14     Completed Date:  1989-08-14     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  8207790     Medline TA:  Clin Exp Hypertens A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  389-95     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Keio University, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Ambulatory Care
Blood Pressure
Blood Pressure Determination / methods
Epinephrine / urine
Heart Rate
Humans
Hypertension / physiopathology*
Norepinephrine / urine
Self Care
Sympathetic Nervous System / physiopathology*
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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