Document Detail

Increased risk of lead fracture and migration in dystonia compared with other movement disorders following deep brain stimulation.
MedLine Citation:
PMID:  14975410     Owner:  NLM     Status:  MEDLINE    
Deep brain stimulation (DBS) therapy is a continually expanding field in the functional neurosurgical treatment of movement disorders. However, the occurrence of adverse events related to implanted hardware cannot be overlooked. We report on a specific feature noted in our experience of DBS-related complications. From 1998 until present we have found an overall rate of 5.3% of DBS electrode lead dysfunction (out of 133 patients) in our series (slipped leads 2.3%, lead fracture 3.8%). Interestingly, all of these failures occurred in dystonia patients (18.4% of all dystonia patients and 9.2% of all electrodes). We postulate on mechanisms that may explain why these complications predominate in this group of patients.
J Yianni; D Nandi; A Shad; P Bain; Ralph Gregory; Tipu Aziz
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  11     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-02-20     Completed Date:  2007-06-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
The Oxford Movement Disorder Group, Department of Neurological Surgery, The Radcliffe Infirmary, Oxford OX2 6HE, UK.
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MeSH Terms
Aged, 80 and over
Deep Brain Stimulation / adverse effects*,  instrumentation
Dystonia / complications*,  therapy
Electrodes / adverse effects*
Equipment Failure*
Foreign-Body Migration / etiology*
Middle Aged
Movement Disorders / complications*,  therapy
Neurosurgical Procedures
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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