| Increased risk of death associated with hypotension is not altered by the presence of brain injury in pediatric trauma patients. | |
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MedLine Citation:
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PMID: 18005764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hypotension is a well-known predictor of mortality in pediatric trauma patients. However, it is unknown whether the mortality rate is higher in patients with traumatic brain injury (TBI) than in those without TBI. We hypothesized that systemic hypotension increases mortality in pediatric patients with TBI more than it does in pediatric patients with extracranial injuries only. METHODS: Multivariate logistic regression was used to determine the relationship between hypotension and the risk of death. Patients were then divided into 2 groups: TBI and No-TBI and the model was applied separately to each group. RESULTS: Overall mortality was 2%. After adjusting for confounding variables, hypotension remained a strong independent predictor of mortality. However, the increased risk of death was similar in patients with and without TBI. CONCLUSION: Hypotension is an important predictor of death in pediatric trauma patients. The increased risk of death associated with hypotension is similar with or without traumatic brain injury. |
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Authors:
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Mark A Gunst; Jason L Sperry; Vafa Ghaemmaghami; Richard F Gunst; Randall S Friese; Heidi L Frankel; Larry M Gentilello; Shahid Shafi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of surgery Volume: 194 ISSN: 1879-1883 ISO Abbreviation: Am. J. Surg. Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-11-16 Completed Date: 2007-12-11 Revised Date: 2009-05-20 |
Medline Journal Info:
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Nlm Unique ID: 0370473 Medline TA: Am J Surg Country: United States |
Other Details:
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Languages: eng Pagination: 741-4; discussion 744-5 Citation Subset: AIM; IM |
Affiliation:
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Division of Burns, Trauma and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390-9158, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Area Under Curve Brain Injuries / epidemiology*, mortality Child Child, Preschool Female Humans Hypotension / epidemiology*, mortality Infant Infant, Newborn Logistic Models Male Odds Ratio Risk Assessment |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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