Document Detail

Increased risk of brain injury in IVF babies.
MedLine Citation:
PMID:  22075798     Owner:  NLM     Status:  In-Data-Review    
AIM: The aim of this paper was to assess brain injury occurrence among in vitro fertilization (IVF) babies.
METHODS: We examined all babies born in our hospital in the triennium 2004-2006, comparing the presence of brain injuries between IVF babies and the rest of the population.
RESULTS: In IVF group (180 babies), brain injury was present in 4 babies, while in the rest of population (n=3602) it was present in 23 babies (P=0.042, RR: 3.18). IVF babies have a higher risk of being born with a birthweight less than 2 500 grams (P<0.0001; RR: 5.133). When we considered only babies born with a birth weight less than 2 500 grams, the difference of brain injury between the two groups was not significant.
CONCLUSION: In IVF babies, brain injury occurred more frequently than in the rest of population. This is probably due to a higher rate of premature births and low birth weight in IVF population. Anyway, this data should be disclosed to future parents to make an informed decision.
C V Bellieni; F Bagnoli; M Tei; M De Filippo; S Perrone; G Buonocore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva pediatrica     Volume:  63     ISSN:  0026-4946     ISO Abbreviation:  Minerva Pediatr.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400740     Medline TA:  Minerva Pediatr     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  445-8     Citation Subset:  IM    
Department of Pediatrics Obstetrics and Reproduction Medicine, University of Siena, Siena, Italy -
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