Document Detail

Increased prevalence of primary hyperparathyroidism in treated breast cancer.
MedLine Citation:
PMID:  11407650     Owner:  NLM     Status:  MEDLINE    
IN CONCLUSION: 1) an increased frequency of parathyroid adenoma was found in BC patients with mildly aggressive neoplastic disease; 2) in BC patients with no evidence of primary hyperparathyroidism mean serum PTH and calcium concentrations were significantly greater than in healthy controls and in patients with thyroid carcinoma; and 3) this finding was unrelated to clinical staging or anti-tumor therapy. Thus, primary hyperparathyroidism should be considered as a possible cause of hypercalcemia in patients with non-aggressive breast cancer. We suggest that serum PTH should be determined in all BC patients with increased serum calcium concentration, especially in those with no evidence of metastatic disease.
P Fierabracci; A Pinchera; P Miccoli; P F Conte; E Vignali; M Zaccagnini; C Marcocci; C Giani
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  24     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-15     Completed Date:  2001-10-11     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
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MeSH Terms
Adenoma / complications,  surgery
Aged, 80 and over
Bone Neoplasms / secondary
Breast Neoplasms / complications*,  pathology,  therapy*
Calcium / blood
Carcinoma / blood,  pathology,  surgery
Hypercalcemia / etiology
Hyperparathyroidism / complications,  epidemiology*
Middle Aged
Neoplasm Metastasis
Neoplasm Staging
Parathyroid Hormone / blood
Parathyroid Neoplasms / complications,  surgery
Thyroid Neoplasms / blood,  pathology,  surgery
Reg. No./Substance:
0/Parathyroid Hormone; SY7Q814VUP/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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