| Increased prevalence of concentric left ventricular hypertrophy in African-Americans: will an epidemic of heart failure follow? | |
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MedLine Citation:
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PMID: 17131073 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Left ventricular hypertrophy (LVH), used in this review to denote abnormally increased left ventricular (LV) mass, is an important cardiac trait because of its association with numerous adverse cardiovascular outcomes including myocardial infarction and heart failure. LV mass is typically assessed by noninvasive cardiac imaging (echocardiography or MRI); electrocardiography is an insensitive measure. There are two predominant types of hypertrophy: concentric, where LV wall thickness is increased relative to cavity dimensions, and eccentric, where LV wall thickness is not increased relative to cavity dimensions. Several large studies indicate that the prevalence of concentric LVH is higher in African-Americans versus whites. Although there are data to suggest that concentric LVH results in systolic heart failure in animal models, such data are lacking in humans. How concentric LVH affects the prevalence of systolic and diastolic heart failure in African-Americans needs further study. Given the large burden of LVH among African-Americans, such data are needed to estimate the expected burden and type of heart failure which will occur in the future in this population. |
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Authors:
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Sandeep Kamath; David Markham; Mark H Drazner |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Heart failure reviews Volume: 11 ISSN: 1382-4147 ISO Abbreviation: Heart Fail Rev Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-28 Completed Date: 2007-01-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9612481 Medline TA: Heart Fail Rev Country: United States |
Other Details:
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Languages: eng Pagination: 271-7 Citation Subset: IM |
Affiliation:
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Donald W. Reynolds Cardiovascular Clinical Research Center and Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Continental Ancestry Group / statistics & numerical data* Female Health Transition Heart Failure / etiology* Humans Hypertrophy, Left Ventricular / complications, epidemiology*, ethnology Male Middle Aged Prevalence United States / epidemiology |
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