Document Detail

Increased physiological dead space/tidal volume ratio during exercise in burned children.
MedLine Citation:
PMID:  7546253     Owner:  NLM     Status:  MEDLINE    
Exercise testing enables the simultaneous evaluation of the cardiovascular and respiratory systems' ability to perform gas exchange. The physiological responses to exercise have not been previously reported in the postburn child. This investigation was designed to evaluate residual cardiopulmonary impairment in patients convalescing from severe burns. Spirometry, lung volumes and exercise stress testing were completed on 40 children with a mean time postburn injury of 2.6 +/- 1.9 years and mean burn size of 44 +/- 22 per cent TBSA. Respiratory variables studied during exercise included expired volume, tidal volume and respiratory rate, and physiological dead space/tidal volume (VD/VT) ratios. Stress testing revealed an increased VD/VT ratio consistent with uneven ventilation-perfusion relationships. The data indicate that patients who survive thermal injury may not regain normal cardiopulmonary homeostasis.
R P Mlcak; M H Desai; E Robinson; R L McCauley; J Richardson; D N Herndon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  21     ISSN:  0305-4179     ISO Abbreviation:  Burns     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-11-20     Completed Date:  1995-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  337-9     Citation Subset:  IM    
Shriners Burns Institute, Galveston, Texas, USA.
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MeSH Terms
Burns / physiopathology*
Exercise Test*
Lung Volume Measurements
Respiratory Dead Space*
Tidal Volume*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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