Document Detail


Increased one-year risk of symptomatic venous thromboembolism following total hip replacement: A nationwide cohort study.
MedLine Citation:
PMID:  23188898     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We examined the one-year risk of symptomatic venous thromboembolism (VTE) following primary total hip replacement (THR) among Danish patients and a comparison cohort from the general population. From the Danish Hip Arthroplasty Registry we identified all primary THRs performed in Denmark between 1995 and 2010 (n = 85 965). In all, 97% of patients undergoing THR received low-molecular-weight heparin products during hospitalisation. Through the Danish Civil Registration System we sampled a comparison cohort who had not undergone THR from the general population (n = 257 895). Among the patients undergoing THR, the risk of symptomatic VTE was 0.79% between 0 and 90 days after surgery and 0.29% between 91 and 365 days after surgery. In the comparison cohort the corresponding risks were 0.05% and 0.12%, respectively. The adjusted relative risks of symptomatic VTE among patients undergoing THR were 15.84 (95% confidence interval (CI) 13.12 to 19.12) during the first 90 days after surgery and 2.41 (95% CI 2.04 to 2.85) during 91 to 365 days after surgery, compared with the comparison cohort. The relative risk of VTE was elevated irrespective of the gender, age and level of comorbidity at the time of THR. We concluded that THR was associated with an increased risk of symptomatic VTE up to one year after surgery compared with the general population, although the absolute risk is small.
Authors:
A B Pedersen; S P Johnsen; H T Sørensen
Related Documents :
9351758 - Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: result...
17402278 - Health risks in wastewater irrigation: comparing estimates from quantitative microbial ...
15530628 - Regression of low-grade squamous intra-epithelial lesions in young women.
15122518 - Relationship between smoking and human papillomavirus infections in hiv-infected and -u...
20872148 - The prevalence of chlamydia trachomatis and neisseria gonorrhoeae in the endocervical s...
20147658 - Migraine and cardiovascular disease: a population-based study.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of bone and joint surgery. British volume     Volume:  94     ISSN:  0301-620X     ISO Abbreviation:  J Bone Joint Surg Br     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375355     Medline TA:  J Bone Joint Surg Br     Country:  England    
Other Details:
Languages:  eng     Pagination:  1598-603     Citation Subset:  AIM; IM    
Affiliation:
Aarhus University Hospital, Department of Clinical Epidemiology, Olof Palmes Allé 43-45, DK-8200 Aarhus N, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Patient safety in orthopaedics: State of the art.
Next Document:  Cemented polyethylene and cementless porous-coated acetabular components have similar outcomes at a ...