Document Detail


Increased neonatal mortality among normal-weight births beyond 41 weeks of gestation in California.
MedLine Citation:
PMID:  18639211     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to examine whether postterm gestational age increases the risk of neonatal mortality. STUDY DESIGN: We retrieved data from 1,815,811 liveborn infants in California from 1999 to 2003. We excluded multiple births and congenital anomalies, as well as infants with a gestational age of less than 38 w0d, or greater than 42 w6d, weeks. We used multivariable logistic regression models to adjust for demographic variables thought to confound the association. RESULTS: Compared to infants born at 38, 39, or 40 weeks, those born at 41 w0d to 42 w6d have a greater odds of neonatal mortality (aOR: 1.34, 95% CI, 1.08-1.65). Subdividing by gestational week, infants delivered at 41 w0d to 41 w6d showed elevated mortality relative to earlier term births (aOR: 1.37, 95% CI, 1.08-1.73). Additional analyses support this increased neonatal mortality across all normal birthweight categories. CONCLUSION: Infants born beyond 41 w0d of gestation experience greater neonatal mortality relative to term infants born between 38 w0d and 40 w6d.
Authors:
Tim A Bruckner; Yvonne W Cheng; Aaron B Caughey
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.     Date:  2008-07-17
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  199     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-20     Completed Date:  2008-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  421.e1-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Epidemiology, University of California, Berkeley, School of Public Health, Berkeley, CA, USA. brucknet@berkeley.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
California / epidemiology
Female
Gestational Age*
Humans
Infant Mortality*
Infant, Newborn
Logistic Models
Male
Odds Ratio
Placental Insufficiency / epidemiology
Pregnancy
Pregnancy Outcome*
Retrospective Studies
Socioeconomic Factors
Grant Support
ID/Acronym/Agency:
HD01262/HD/NICHD NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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