| Increased neonatal morbidity despite pulmonary maturity for deliveries occurring before 39 weeks. | |
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MedLine Citation:
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PMID: 22963341 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objective: To compare neonatal outcomes following deliveries <39 weeks after confirmation of fetal lung maturity with scheduled deliveries ≥39 weeks. Methods: A retrospective cohort study examining neonatal outcomes of women who were delivered following documented fetal pulmonary maturity at 36, 37, and 38 weeks compared to women undergoing a scheduled delivery at 39, 40, and 41 weeks. The chi square test and Student t test were used to compare categorical and continuous data respectively. Results: Delivery prior to 39 weeks following fetal pulmonary maturity was associated with a 8.4 % composite neonatal morbidity rate as compared to 3.3% for deliveries at 39 weeks or greater (relative risk [RR] 2.9; confidence interval [CI] 2.4-3.6). Neonatal respiratory morbidity was significantly higher (5.4%) for those delivering at less than 39 weeks with documented fetal pulmonary maturity as compared to 2.1% for those delivering at 39 weeks or greater (RR 3.0; CI 2.3-3.9). Increased neonatal morbidity persisted for those delivered prior to 39 weeks even after excluding all diabetics (p<.001). Significant increases in neonatal morbidity were noted for deliveries prior to 39 weeks regardless of the mode of delivery. Conclusion: Despite fetal pulmonary maturity, delivery before 39 weeks is associated with significantly increased neonatal morbidity when compared to scheduled deliveries at 39 weeks or greater. |
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Authors:
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Yu Ming Victor Fang; Peter Guirguis; Adam Borgida; Deborah Feldman; Charles Ingardia; Victor Herson |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-11 |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Hartford Hospital, Hartford, Connecticut. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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