Document Detail

Increased mitral-aortic separation in discrete subaortic stenosis.
MedLine Citation:
PMID:  571775     Owner:  NLM     Status:  MEDLINE    
We recently speculated that mitral-aortic separation (MAS) might be increased in discrete subaortic stenosis (DSS). We have examined this hypothesis in 22 heart specimens in which the subaortic obstruction originated on the muscular ventricular septum below the right aortic sinus, either as a discrete band, an accumulation of several bands or a diffuse ridge, and extended posteriorly into the MAS or anterior leaflet of the mitral valve or both, with a variable relationship to the aortic cusps and sinuses. No specimen had ventricular septal defect, supravalvular aortic stenosis or other features of Shone syndrome. The mean MAS was nearly twice that of 80 normal specimens (4.9 vs 2.5 mm), the range of MAS was increased from normal (0.11 vs 0.7 mm) and the mean diameter of the aortic annulus was decreased compared with the normal specimens, data that will be of interest to echo- and angiocardiographers in the clinical description of DSS, and to the surgeon who must resect these lesions.
G C Rosenquist; E B Clark; H A McAllister; S Bharati; J E Edwards
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  60     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-08-16     Completed Date:  1979-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  70-4     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Stenosis, Subvalvular / congenital*,  pathology
Aortic Valve / abnormalities*,  pathology
Cardiomyopathy, Hypertrophic / congenital*
Heart Septum / pathology
Mitral Valve / abnormalities,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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